Scientist, Process Development and Analytical

Posté 01 déc. 2021

St. Louis, Missouri - United States

Demander un identifiant 234416



A career with MilliporeSigma is an ongoing journey of discovery: our 58,000 people are shaping how the world lives, works and plays through next generation advancements in Healthcare, Life Science and Electronics. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany.



US employees must be fully vaccinated against COVID-19 prior to your start date unless an accommodation is granted by The Company. The Company uses the definition of fully vaccinated assigned by the Centers for Disease Control & Prevention for purposes of considering satisfaction of this requirement which is a condition of employment.


Your Role: 

At MilliporeSigma, the Process Development Scientist reports to the Bioconjugaton Manager in contract manufacturing sector. The Process Development Scientist will work in the Process and Analytical Development department to develop process chemistry for transfer to GMP manufacturing.

The position will center around development/optimization, development scale-up campaigns and technology transfer designed to deliver robust and cost-effective production processes to GMP manufacturing.


  • Work with a team of bioprocess and bioanalytical scientists to develop Bioconjugation process chemistry.
  • Leverage experience in bioconjugation chemistry to on-board/develop, optimize, and scale-up process chemistry unit operations.
  • Effectively work with key stakeholders to technology transfer time-sensitive production processes to GMP manufacturing.
  • Troubleshoot process non-conformances and deliver data-driven solutions.



Who You Are:


Minimum Qualifications:

  • Bachelor’s Degree in Chemistry, Biochemistry, Biology or other related Scientific discipline


Preferred Qualifications:

  • 3+ years’ Experience in bioconjugation chemistry development and optimization, including the use of Design of Experiments
  • 3+ years’ Experience with ADC development and purification on a preparative scale
  • Experience with PAT
  • Attention to detail in planning, execution, and documentation of experimental work
  • Exemplary communication skills including timely and concise written and oral communications to both external and internal project stakeholders
  • Willing to work occasional extended days and weekend shifts for special projects








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Our Benefits -

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