Principal Scientist, Immuno-Oncology

Posted 28 Feb 2022

Billerica, Massachusetts - United States

Req Id 242154



A career with EMD Serono is an ongoing journey of discovery: our 58,000 people are shaping how the world lives, works and plays through next generation advancements in Healthcare, Life Science and Electronics. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. EMD Serono is a business of Merck KGaA, Darmstadt, Germany.



US employees must be fully vaccinated against COVID-19 prior to your start date unless an accommodation is granted by The Company. The Company uses the definition of fully vaccinated assigned by the Centers for Disease Control & Prevention for purposes of considering satisfaction of this requirement which is a condition of employment.


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United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.


This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 


Your Role:

At EMD Serono an exciting new opportunity has arisen within the Immuno-Oncology group focusing on the development of novel therapeutics that modulate the immune system to attack tumors. In this role, the candidate is expected to conduct in-vitro cellular/immune assays to deconvolute MOA and develop biomarker assays to support target modulation readouts (PD) and patient/indication selection using human/mouse pre-clinical and clinical tumor material. Responsibilities will include detailed development and precise implementation of in-vitro cell-based assay systems, critical data analysis, meticulous data recording and presentation of data.


Who you are:
Minimum Qualifications:

  • PhD degree in a relevant scientific field (e.g. immunology, cancer immunology, cancer biology) with minimum of 5 years of post-doctoral experience in the relevant scientific field in an academic and/or industry setting. The experience in developing cancer immunotherapeutic in industry setting is highly desired. 


Preferred Qualifications:

  • PhD in Immunology and/or Cancer Biology  
  • Consistent record of cutting edge research in cancer biology, immunology or a relevant scientific field, as evidenced by a strong publication record.
  • Experience in managing team(s) with previous demonstrated ability to work as an effective leader.
  • Hands on experiences in and detailed knowledge of in vitro and ex vivo cell based assay development in the field related to oncology and immunology. 
  • High proficiency with immuno-assays including IHC and pre-clinical biomarkers,  flow cytometry, cytotoxicity assays, cytokine release assays, IncuCyte live cell imaging, etc.
  • Molecular Biology: qPCR, Western blotting, ELISA
  • Meta-analysis of data from public databases
  • Experience in managing academic research collaborations is preferred. 
  • Excellent communication, organization and multitasking ability combined with the capacity to quickly adapt to project priorities to deliver data packages according to established timelines
  • Ability to interact with senior management in matrix organization
  • Forward-thinking and creative with high ethical standards
  • Track record of scientific accomplishment and publications in the advancement of new therapeutic concepts
  • Capacity for providing intellectual input, creative insight and assisting in the design of project work-plans
  • Ability to work independently and as part of multidisciplinary project teams


What we offer: With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!

Our Benefits -

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If you are a resident of a Connecticut or Colorado, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.


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