Principal Scientist/Project Lead (all genders) Medicinal Chemistry

Posted 14 Dec 2021

Darmstadt, Hessen - Germany

Req Id 236443



A career at our company is an ongoing journey of discovery: our 58,000 people are shaping how the world lives, works and plays through next generation advancements in Healthcare, Life Science and Electronics. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others.


United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.


Your role: 

You will be a member of the medicinal chemistry group at our main research site in Darmstadt, located in the thriving greater Frankfurt area, Germany. In this role, you will lead a medicinal chemistry laboratory with 2-3 direct reports and drive innovative drug discovery projects towards identification of clinical candidates for oncology, immune-oncology, and immunology indications. You will be responsible for defining and executing project strategies, coordinating multi-parameter lead optimization programs and lead multi-disciplinary project teams in a result-driven & collaborative spirit. You are responsible for driving the project progress through design and synthesis of new test compounds. Applying modern synthesis methodologies, you are ensuring compound supply and synthesis scalability. Your tasks will include enhancing our external visibility and scientific excellence through publishing, collaborating with the scientific community, and contributing to conferences. Your personal development will be supported by training adapted to your professional interests and needs. 


Who you are: 

  • PhD degree in chemistry and preferably 3-5 years of relevant prior industrial experience 

  • Sound knowledge and practical experience of synthetic organic chemistry, passionate about the use of synthetic chemistry to address key questions in the field of life sciences 

  • Broad medicinal chemistry expertise & track record of successful medicinal chemistry optimization projects 

  • Demonstrated high level of creativity and independence in solving complex scientific problems, experienced in working in a dynamic environment and within a multidisciplinary & international team 

  • Excellent communication skills, fluent in English (written and spoken); excellent presentation skills; interested in sharing skills, knowledge, and enthusiasm by supporting and teaching junior staff 


What we offer:  With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!


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