Principal Process Scientist

Posted 06 Dec 2021

St. Louis, Missouri - United States

Req Id 235987

Details

 

A career with MilliporeSigma is an ongoing journey of discovery: our 58,000 people are shaping how the world lives, works and plays through next generation advancements in Healthcare, Life Science and Electronics. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany.    

 

US employees must be fully vaccinated against COVID-19 prior to your start date unless an accommodation is granted by The Company. The Company uses the definition of "fully vaccinated" assigned by the Centers for Disease Control & Prevention for purposes of considering satisfaction of this requirement which is a condition of employment.

 


Your Role:

MilliporeSigma has an opening for a Principal Process Scientist in our St. Louis, MO location; this is an onsite opportunity with work flexibility. Reporting to the Head of Novel Modalities R&D, the Principal Process Scientist will work on the development of innovative manufacturing technologies for RNA lipid nanoparticles / liposomes. You will drive innovation for R&D activities securing IP for internal MilliporeSigma technology and product platforms whenever suitable. You will be responsible for identifying optimized solutions while considering the newest scientific data sources and interactions with the scientific community. You will also be responsible for staying updated on product and industry knowledge as well as “best-in-class” manufacturing technologies.

Additional responsibilities include:

  • Leading the development efforts to deliver project breakthroughs on-time and on-quality
  • Drive implementation of digital tools and solutions in the development and manufacturing fields.
  • Establish a team-based approach with other internal organizations, such as marketing, sales, PAD, QC and Manufacturing.
  • Establish relationships in the industry that provide access to direct customer feedback and create opportunities for extraordinary responsiveness and innovative growth.
  • Deliver timely and comprehensive written and oral communications to both internal and external partners
  • Demonstrate attention to detail in the planning, execution, and documentation of experimental work

Who You Are:

Minimum Qualification:

  • PhD. Degree in chemistry, chemical engineering, biochemistry, biology, or other related scientific subject area
  • > 8 years of hands-on experience in the preparation of liposome / lipid nanoparticles (LNP) in an R&D or process development environment
  • > 3 years of industrial experience with encapsulating RNA in lipid nanoparticles using ethanol injection method
  • > 3 years of process development experience for large scale liposomes or lipid nanoparticles formation and purification operation

Preferred Qualifications:

  • Ph.D. with 5+ years of working experience in the cGMP/GLP environment in a CMO or CRO
  • Experience with technology transfer and scale-up to cGMP manufacturing process
  • Experience with RNA therapeutic drugs
  • Experience with high-throughput process development techniques and statistical design of experiments (DoE)
  • Ability to train and mentor employees

 

What we offer: With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!

Our Benefits - http://jobs.vibrantm.com/emd/content/Benefits-at-a-Glance/?locale=en_US

Curious? Apply and find more information at https://jobs.vibrantm.com

If you are a resident of a Connecticut or Colorado, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

 

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